Description and Brand Names
Drug information provided by: IBM Micromedex
US Brand Name
- Pulmicort Flexhaler
- Pulmicort Respules
- Pulmicort Turbuhaler
Canadian Brand Name
- Pulmicort
- Pulmicort Nebuamp
- Rhinocort Turbuhaler
Descriptions
Budesonide is used to help prevent the symptoms of asthma. When used regularly every day, inhaled budesonide decreases the number and severity of asthma attacks. However, it will not relieve an asthma attack that has already started.
Budesonide is a corticosteroid or steroid (cortisone-like medicine). It works by preventing inflammation (swelling) in the lungs, which makes the asthma attack less severe. Inhaled budesonide may be used with other asthma medicines such as bronchodilators, which are also used to open up narrowed breathing passages in the lungs.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
- Suspension
- Powder
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Pulmicort Respules® in children 12 months to 8 years of age. However, safety and efficacy have not been established in children younger than 12 months of age.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Pulmicort Flexhalerâ„¢ in children 6 years of age and older. However, safety and efficacy have not been established in children younger than 6 years of age.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of inhaled budesonide in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment in the dose for patients receiving inhaled budesonide.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Desmopressin
- Levoketoconazole
- Rotavirus Vaccine, Live
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aceclofenac
- Acemetacin
- Adagrasib
- Amtolmetin Guacil
- Balofloxacin
- Belzutifan
- Bemiparin
- Besifloxacin
- Boceprevir
- Bromfenac
- Bufexamac
- Bupropion
- Celecoxib
- Ceritinib
- Choline Salicylate
- Ciprofloxacin
- Clarithromycin
- Clonixin
- Cobicistat
- Conivaptan
- Cyclosporine
- Darunavir
- Dexibuprofen
- Dexketoprofen
- Diclofenac
- Diflunisal
- Dipyrone
- Droxicam
- Duvelisib
- Enoxacin
- Etodolac
- Etofenamate
- Etoricoxib
- Fedratinib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Fexinidazole
- Fleroxacin
- Floctafenine
- Flufenamic Acid
- Flumequine
- Flurbiprofen
- Fosnetupitant
- Gatifloxacin
- Gemifloxacin
- Ibuprofen
- Idelalisib
- Indinavir
- Indomethacin
- Itraconazole
- Ivosidenib
- Ketoconazole
- Ketoprofen
- Ketorolac
- Larotrectinib
- Lefamulin
- Levofloxacin
- Lomefloxacin
- Lorlatinib
- Lornoxicam
- Loxoprofen
- Lumacaftor
- Lumiracoxib
- Lutetium Lu 177 Dotatate
- Macimorelin
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Morniflumate
- Moxifloxacin
- Nabumetone
- Nadifloxacin
- Nadroparin
- Naproxen
- Nefazodone
- Nelfinavir
- Nepafenac
- Netupitant
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nirmatrelvir
- Norfloxacin
- Ofloxacin
- Olutasidenib
- Oxaprozin
- Oxyphenbutazone
- Pacritinib
- Parecoxib
- Pazufloxacin
- Pefloxacin
- Phenylbutazone
- Piketoprofen
- Piroxicam
- Posaconazole
- Pranoprofen
- Proglumetacin
- Propyphenazone
- Proquazone
- Prulifloxacin
- Ritonavir
- Rofecoxib
- Rufloxacin
- Salicylic Acid
- Salsalate
- Saquinavir
- Sargramostim
- Sodium Salicylate
- Sparfloxacin
- Sulindac
- Telaprevir
- Telithromycin
- Tenoxicam
- Tiaprofenic Acid
- Tolfenamic Acid
- Tolmetin
- Tosufloxacin
- Valdecoxib
- Voriconazole
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Auranofin
- Erythromycin
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Grapefruit Juice
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma attack, acute—Should not be used in patients with this condition.
- Bone problems (e.g., osteoporosis) or
- Cataracts or
- Glaucoma—Use with caution. May make these conditions worse.
- Chickenpox, including recent exposure or
- Measles or
- Herpes simplex virus infection of the eye or
- Infections (virus, bacteria, or fungus) or
- Tuberculosis, active or history of—This medicine can reduce the body's ability to fight off these infections.
- Milk protein allergy, severe—Use with caution. The Pulmicort Flexhaler™ contains lactose (milk sugar with milk protein), which may cause side effects for patients with this condition.
Proper Use
Inhaled budesonide is used to prevent asthma attacks. It is not used to stop an attack that has already started. For relief of an asthma attack that has already started, you or your child should use another medicine. If you do not have another medicine to use for an acute asthma attack or if you have any questions about this, check with your doctor.
Use this medicine only as directed. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop taking this medicine without telling your doctor. To do so may increase the chance of side effects.
In order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor. This medicine usually begins to work in about 24 to 48 hours, but up to 2 to 6 weeks may pass before you feel the full effects.
Do not change your dose or stop using this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous.
When using the Pulmicort Flexhalerâ„¢:
- This medicine comes as a powder that you breathe into the lungs with a special inhaler that is placed in the mouth. It is used by adults, teenagers, and children who are 6 years of age and older.
- The medicine comes with patient instructions. Read the instructions carefully before using this medicine. If you or your child do not understand the instructions or are not sure how to use the inhaler, check with your doctor.
- When you use the inhaler for the first time, it may not deliver the right amount of medicine with the first puff. Before using this medicine, test or prime it.
- Hold the inhaler so that the white cover points up, then twist the cover and lift it off. Hold the inhaler upright (mouthpiece up) using the brown grip, then twist the middle of the inhaler fully in one direction as far as it will go, and then back again in the other direction. You will hear a click. Repeat this process one more time.
- You do not have to prime it again after this, even if you have not used it for a long time.
- After the inhaler is primed, twist the cover and lift it off.
- To load a dose, hold the inhaler in the upright position, then twist the grip fully in one direction as far as it will go, and then fully back again in the other direction. You will hear a click.
- Turn your head away from the inhaler and breathe out. Do not shake the inhaler.
- Place the mouthpiece between your lips and breathe in deeply and forcefully. You may not taste or feel the medicine.
- Do not chew or bite on the mouthpiece.
- Remove the inhaler from your mouth and breathe out. Do not blow or breathe into the inhaler.
- Repeat these steps if more than one dose is needed.
- When you are finished, place the cover back on the inhaler and twist shut. Rinse your mouth with water and spit out the water. Do not swallow the water. This helps prevent hoarseness, throat irritation, and infections in the mouth.
- Do not use the inhaler if it has been damaged or if the mouthpiece has become detached.
- Do not use a spacer with the Pulmicort Flexhalerâ„¢.
- Keep the inhaler clean and dry at all times. Follow the patient directions for cleaning and storing the inhaler.
- The inhaler has a dose indicator that keeps track of how many times you can use the inhaler before you need to open a new one. Check the dose indicator just below the mouthpiece. The dose indicator usually starts with either the number 60 or 120 when full.
- Discard the whole device when all doses have been used. The inhaler is empty when the number zero appears in the middle of the dose indicator window. You will be given a new inhaler each time you refill your prescription.
When using the Pulmicort Respules® liquid:
- This medicine comes as a liquid that you breathe into the lungs with a special breathing machine called a jet nebulizer. The nebulizer has a face mask or mouthpiece. It is used by children who are 12 months to 8 years of age.
- Your doctor will tell you which type of nebulizer to use with this medicine and will show you how to use the nebulizer. The medicine and nebulizer come with patient instructions. Read the instructions carefully before using the medicine or the machine. If you or your child do not understand the instructions or are not sure how to use the nebulizer, check with your doctor.
- Use this medicine at the same time each day, unless your child's doctor tells you otherwise.
- Do not mix this liquid with other medicines.
- Open the sealed aluminum foil envelope containing the medicine. Remove one container from the strip of five plastic containers with sealed caps. Write the current date on the back of the envelope when you open the foil pouch.
- Each container has one dose of medicine.
- Place the unused containers back in the foil pouch. This will protect the medicine from light.
- Shake the container in a circular motion before using it.
- Hold the container upright and open it by twisting off the cap.
- Slowly squeeze out all of the contents of the container into the nebulizer cup. Throw the empty container away.
- If your child is using a face mask, make sure that the mask fits tightly on the face to avoid getting the medicine in the eyes.
- Turn on the compressor to begin nebulizing the medication. The nebulizer turns the medicine into a fine mist that the child breathes into the lungs using the mouthpiece or mask.
- After the dose is completed, wash your child's face to prevent skin irritation.
- Rinsing your child's mouth with water after each dose may help prevent hoarseness, throat irritation, and infections in the mouth. Do not allow your child to swallow the water after rinsing.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For preventing an asthma attack:
- For inhalation dosage form (powder inhaler):
- Adults and children 6 years of age and older—At first, one or two puffs two times a day. Your doctor may increase your dose as needed.
- Children younger than 6 years of age—Use and dose must be determined by your doctor.
- For inhalation dosage form (suspension in a nebulizer):
- Children 12 months to 8 years of age—0.5 to 1 milligram (mg) in a nebulizer once a day, or divided and given twice a day. Each container of liquid has one dose and a new container is used for each dose.
- Infants younger than 12 months of age—Use and dose must be determined by your doctor.
- For inhalation dosage form (powder inhaler):
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Store the Pulmicort Flexhalerâ„¢ in a dry place at room temperature with the cover tightly in place.
Store the unused Pulmicort Respules® in an upright position at room temperature. Keep the medicine containers in the foil pouch until you are ready to use them. Do not freeze the containers. Once you have opened a foil pouch, the containers will only be good for 2 weeks. Throw away any unused containers if it has been longer than 2 weeks since you opened the pouch.
Precautions
It is very important that your doctor check you or your child's progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects caused by this medicine.
You or your child should not use this medicine if your asthma attack has already started. Your doctor will prescribe another medicine (e.g., a short-acting inhaler) for you to use in case of an acute asthma attack. Call your doctor if you have any questions about this.
If your or your child's symptoms do not improve within one to two weeks, or if they become worse, check with your doctor.
This medicine may weaken your immune system. Avoid being around people who are sick or who have infections such as chickenpox or measles. Tell your doctor right away if you think you or your child have been exposed to chickenpox or measles.
If you or your child develop a skin rash, hives, or any type of allergic reaction (including anaphylaxis) to this medicine, stop using the medicine and check with your doctor as soon as possible.
This medicine may also increase your risk of having infections or sores in your mouth or throat. Check with your doctor right away if you or your child have any signs of a throat infection.
This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, talk to your doctor.
This medicine may cause children to grow more slowly than normal. This would cause a child to not gain weight or get taller. Talk with your child's doctor if you think this is a problem or if you have any concerns.
This medicine may increase your risk of having an adrenal gland that is less active than normal. The adrenal gland makes steroids for your body. This is more likely for people who use steroids for a long time or use high doses. Check with your doctor right away if you or your child have more than one of the following symptoms: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. Rarely, menstrual cycle changes, acne, pimples, or weight gain (fat deposits) around the face, neck, and trunk may occur while using this medicine.
Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you or your child to have your eyes checked by an ophthalmologist (eye doctor).
Make sure any doctor or dentist knows that you or your child are using this medicine. You might need to stop using this medicine several days before having surgery.
Your doctor may want you or your child to carry a medical identification card that says this medicine is being used. You or your child may need additional medicine during an emergency, a severe asthma attack, an illness, or unusual stress.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Body aches or pain
- chills
- congestion
- cough
- diarrhea
- dryness or soreness of the throat
- fever
- general feeling of discomfort or illness
- headache
- hoarseness
- joint pain
- loss of appetite
- muscle aches and pains
- nausea
- pain or tenderness around the eyes and cheekbones
- shivering
- shortness of breath or troubled breathing
- sneezing
- sore throat
- stuffy or runny nose
- sweating
- tender, swollen glands in the neck
- tightness of the chest or wheezing
- trouble with sleeping
- trouble with swallowing
- unusual tiredness or weakness
- voice changes
- vomiting
Less common
- Bruising
- darkening of the skin
- depression
- dizziness
- earache
- excessive muscle tone
- fainting
- fractures
- large, flat, blue, or purplish patches in the skin
- lower back or side pain
- muscle stiffness
- muscle tension or tightness
- painful or difficult urination
- redness or swelling in the ear
- skin rash
- sore mouth or tongue
- white patches in the mouth or on the tongue
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Back pain
Less common
- Acid or sour stomach
- belching
- change in taste or bad, unusual, or unpleasant (after) taste
- difficulty with breathing
- difficulty with moving
- dry mouth
- ear congestion
- headache, severe and throbbing
- heartburn
- indigestion
- muscle cramping
- neck pain
- sleeplessness
- stomach discomfort, upset, or pain
- swollen joints
- unable to sleep
- unexplained runny nose or sneezing
- weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: Feb. 01, 2023
Original article: https://www.mayoclinic.org/drugs-supplements/budesonide-inhalation-route/side-effects/DRG-20071233
Copyright © 2023 IBM Watson Health. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
.
FAQs
What is a common side effect of Nebulised budesonide? ›
Common side effects of budesonide inhalation may include:
fever, sore throat, cough; nausea, vomiting, diarrhea, stomach pain, loss of appetite; nosebleed; or. headache, back pain.
You may notice mood changes and mental health problems while taking budesonide. Talk to your doctor or contact 111 if you have any mood changes including: feeling depressed. feeling high, or moods that go up and down.
What are the side effects of using a nebulizer? ›Side effects of albuterol include nervousness or shakiness, headache, throat or nasal irritation, and muscle aches. More-serious — though less common — side effects include a rapid heart rate (tachycardia) or feelings of fluttering or a pounding heart (palpitations).
What are the precautions of budesonide? ›Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
What is major side effect of inhaled corticosteroids? ›By contrast, there is now increasing concern about the potential systemic effects of inhaled corticosteroids. These putative effects may include adrenal suppression, bone loss, skin thinning, increased cataract formation, decreased linear growth in children, metabolic changes, and behavioral abnormalities.
What is the most common side effect of inhaled corticosteroids? ›Dysphonia — Dysphonia (hoarse voice) is a common complaint among users of inhaled glucocorticoids (ICS).
Is budesonide inhaler harmful? ›Adults taking high doses (either using an inhaler or nebuliser) have an increased risk of getting adrenal gland problems or weak bones (osteoporosis) over time. This is because more of the steroid gets into your body. Your doctor will monitor you closely and may prescribe medicines to help strengthen your bones.
How does budesonide make you feel? ›puffy face, unusual hair growth, mental/mood changes (such as depression, mood swings, agitation), or. slow wound healing.
How do you reduce the side effects of budesonide? ›- Follow instructions. ...
- Tell the prescriber about all medical conditions and medications. ...
- Tell the prescriber about all medications being taken. ...
- Avoid grapefruit and grapefruit juice. ...
- Take calcium and vitamin D supplements. ...
- Avoid infections.
Breathing too rapidly can cause you to hyperventilate, so it is important to breathe at a normal rate. You will usually feel a little dizzy or possibly have tingling in your hands lips or feet. If you notice any of this, stop the treatment and just breathe normally for a few minutes.
What should you not do after a nebulizer? ›
After your nebulization session, don't sterilize the ampoules using heat, as they're made with polycarbonate or plastic. They're materials that are sensitive to heat and you could damage them if you immerse them in boiling water.
Do you breathe in and out through your mouth with a nebulizer? ›Breathe through your mouth until all the medicine is used. This takes 5 to 20 minutes, depending on the device and medicine used. If needed, use a nose clip so that you breathe only through your mouth. Turn off the machine when done.
What are the complications of budesonide? ›- Body aches or pain.
- congestion.
- dryness or soreness of the throat.
- headache.
- muscle aches and pains.
- shortness of breath or troubled breathing.
- sore throat.
- tender, swollen glands in the neck.
you should know that budesonide inhalation sometimes causes wheezing and difficulty breathing immediately after it is inhaled. If this happens, use your fast-acting (rescue) asthma medication right away and call your doctor. Do not use budesonide inhalation again unless your doctor tells you that you should.
What drugs interact with budesonide? ›Some products that may interact with this drug are: aldesleukin, mifepristone, drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).
What is the most common adverse effect of intranasal corticosteroids? ›Intranasal corticosteroids are well tolerated by most patients. The most common adverse effects are a result of local irritation and include dryness, burning, stinging, and epistaxis; in rare cases, nasal septal perforation can occur.
What are three common side effects of corticosteroids? ›Side effects of corticosteroids taken by mouth
A buildup of fluid, causing swelling in your lower legs. High blood pressure. Problems with mood swings, memory, behavior, and other psychological effects, such as confusion or delirium. Upset stomach.
Inhaled steroids are generally well-tolerated and safe at the recommended dosages, even when taken for prolonged periods. However, like all medications there may be side effects. In general, side-effects are more likely to occur at higher doses, though there may be some individual variations.
Which inhaled corticosteroid has the least side effects? ›Nasal corticosteroid sprays help reduce inflammation and are a safe, long-term treatment for most people. Because it has few, if any, side effects, cromolyn is safe to use over long periods of time.
What are the reactions to inhaled steroids? ›Local adverse effects from nasal corticosteroids have ranged from nasal congestion, pruritus, burning, and soreness to perforation of the nasal septum. Inhalation of corticosteroids into the lungs has been reported to cause pruritus, dryness, erythema and oedema of the mouth, a dry cough and odynophagia.
Why do you rinse your mouth after a steroid inhaler? ›
Gargling and rinsing your mouth with water after each dose may help prevent hoarseness, throat irritation, and infection in the mouth. However, do not swallow the water after rinsing. Your doctor may also want you to use a spacer device to lessen these problems.
Is budesonide better than albuterol? ›Albuterol has an average rating of 3.2 out of 10 from a total of 380 ratings on Drugs.com. 19% of reviewers reported a positive effect, while 71% reported a negative effect. Budesonide has an average rating of 6.6 out of 10 from a total of 132 ratings on Drugs.com.
Why was budesonide discontinued? ›AstraZeneca will discontinue the production of PULMICORT® (budesonide) 100 and 200 µg/dose HFA pMDI (pressurised metered dose inhaler) due to complex manufacturing issues related to technical aspects of the device, which prevents the ongoing manufacture of the product.
How long does budesonide inhalation stay in your system? ›How long do they stay in your system? Most inhaled steroids have a beneficial effect for 12 hours. The exceptions are Arnuity Ellipta, Asmanex, and Trelegy Ellipa, which last for 24 hours.
Can budesonide make it hard to sleep? ›Inhaled corticosteroids – medications used as preventers for asthma such as budesonide (Pulmicort) or beclomethasone (Becotide) are usually well tolerated, but can cause insomnia for some people, particularly when used at high doses.
Is fatigue a side effect of budesonide? ›Headache, nausea, abdominal pain, and fatigue have been commonly reported with oral and rectal use.
Does budesonide help immediately? ›In order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor. This medicine usually begins to work in about 24 to 48 hours, but up to 2 to 6 weeks may pass before you feel the full effects.
Can budesonide make you feel sick? ›Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
Is budesonide well tolerated? ›Budesonide has a high first-pass metabolism with minimal systemic absorption. It is therefore felt to cause fewer side effects than traditional glucocorticosteroids and to be generally well tolerated.
Can you stop budesonide nebulizer suddenly? ›Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop taking the drug, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness).
What effect does budesonide have? ›
Budesonide is in a class of medications called corticosteroids. It works by decreasing inflammation (swelling) in the digestive tract of people who have Crohn's disease or in the kidney of people with nephropathy.
How long do budesonide side effects last? ›How long do budesonide side effects last? Mild side effects might improve over time, but it's not guaranteed. Some will last as long as the drug is taken. Others, such as loss of bone density, weight gain, acne, cataracts, and glaucoma could worsen the longer budesonide is taken.
Is high blood pressure a side effect of budesonide? ›Possible side effects: Side effects can include yeast infections (in the mouth or female reproductive organs), urinary tract infections, high blood pressure, high blood sugar levels, weight gain, stretch marks, acne, rounding of the face (moon face), facial hair, difficulty sleeping, mood swings, and psychiatric ...
What drug interacts with budesonide? ›Some products that may interact with this drug are: aldesleukin, mifepristone, drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).
Can you stop taking budesonide cold turkey? ›Do not stop taking budesonide without speaking with your doctor first. This is particularly important if you have been taking budesonide for more than three weeks. Your doctor will want you to reduce your dose gradually when this is necessary, as stopping suddenly can lead to problems.
Is budesonide good for your lungs? ›Budesonide is used to control and prevent symptoms (wheezing and shortness of breath) caused by asthma. This medication belongs to a class of drugs known as corticosteroids. It works directly in the lungs to make breathing easier by reducing the irritation and swelling of the airways.
Can budesonide make breathing worse? ›you should know that budesonide inhalation sometimes causes wheezing and difficulty breathing immediately after it is inhaled. If this happens, use your fast-acting (rescue) asthma medication right away and call your doctor.
Does budesonide affect heart rate? ›For people with heart problems, including high blood pressure: This drug may cause chest pain, high or low blood pressure, fast heart rate, and irregular heart rhythms. These effects may make your heart problem worse. Let your doctor know if you have heart disease.
Who should not use budesonide? ›If your or your child's symptoms do not improve within one to two weeks, or if they become worse, check with your doctor. This medicine may weaken your immune system. Avoid being around people who are sick or who have infections such as chickenpox or measles.
Does budesonide affect kidneys? ›Treatment with budesonide was associated with a 24-month renal function decline of -0.22 (95%CI, -8.2 to 7.8) ml/min/1.73m2, compared to -5.89 (95%CI, -12.2 to 0.4) ml/min/1.73m2 in the corticosteroid treatment group (p = 0.44, for between group difference).